In a healthy individual, the gut is home to an estimated 500 trillion to 1,000 trillion microorganisms, which is far greater than the total number of  human body cells, estimated at around 60 trillion. These microorganisms belong to over 500 species, and their total weight is said to reach as  much as 2 kilograms. When a person is in good health, these gut bacteria coexist in a balanced manner. Interestingly, about one-third of the  weight of human feces is composed of bacteria. Among these microorganisms are bacteria with a variety of characteristics, coexisting in a delicate balance. Human health relies on the  complex chemical transformations carried out by these bacteria, which break down and absorb food, providing the body with essential nutrients.

There are three main types of bacteria in the gut: “beneficial bacteria,” “harmful bacteria,” and “opportunistic bacteria.” The majority of gut bacteria  consist of opportunistic bacteria. As their name suggests, opportunistic bacteria align themselves with the stronger side. When beneficial  bacteria dominate, opportunistic bacteria work alongside them to benefit the body. However, when harmful bacteria outnumber the  beneficial ones, opportunistic bacteria begin to act in ways that are detrimental to health. In this sense, it is no exaggeration to say that health is maintained by the balance of these various types of bacteria. It is also important to note  that 60–70% (previously thought to be only about 30%) of the body’s immune system is concentrated in the gut, making it one of the most vital  organs for maintaining overall health. The key to this balance lies in how to align the majority of opportunistic bacteria with the beneficial bacteria. To achieve this, the primary  approach is to eliminate harmful bacteria from the gut.

However, chemical drugs such as antibiotics and antimicrobial agents have a very broad-spectrum selective toxicity (broad-spectrum antibacterial  activity → effective against a wide range of bacterial species) and indiscriminately attack many beneficial bacteria. In contrast, the antibacterial  and antiviral active component in Strong Manuka Honey, the unique substance methylglyoxal (hereafter referred to as MGO), exhibits highly  precise selective toxicity. As a result, it does not harm normal cells or beneficial bacteria.

Many chemical drugs created by humans are indeed remarkable. However, on the other hand, they often disrupt the balance of gut bacteria (gut flora).  Many of these drugs have very broad-spectrum selective toxicity, which means they also attack beneficial bacteria that are essential for the human body.  This disruption of the gut flora can lead to significant damage to overall health as a result.

The consumption of Strong Manuka Honey is highly effective for maintaining daily health, as well as for the treatment and prevention of a wide  range of diseases. Harmful bacteria and pathogens show remarkable sensitivity to this product. Additionally, its selective toxicity (in this context,  its toxicity toward harmful bacteria—exhibited as antibacterial and antiviral activity) is both precise and supported by a broad-spectrum  antibacterial range (effective against a wide variety of bacterial species). This precise selectivity against beneficial and harmful bacteria is the product’s greatest feature, and it significantly different from  antibiotics and antimicrobial drugs. Unlike antibiotics, which indiscriminately kill both harmful and beneficial bacteria, Strong Manuka Honey  acts exclusively on harmful bacteria. If this were not the case (if it attacked beneficial bacteria as well), consuming this honey would result in the disruption of gut flora due to  its strong antibacterial properties. This would immediately lead to diarrhea and other side effects.

The normal growth environment for beneficial bacteria is slightly acidic, while an alkaline environment becomes a breeding ground for harmful  bacteria. The human body is fundamentally alkaline—muscle tissue and the internal environment of the body are alkaline. However,  the skin, which is in contact with the external environment, and the digestive tract, where harmful bacteria can easily enter, should be  maintained in an acidic state under normal conditions. The stomach achieves this through acid secretion, while the skin, intestines,  and gynecological organs create a protective barrier against harmful external bacteria through acids produced by beneficial bacteria.

Notably, beneficial bacteria in acidic environments neutralize MGO through enzymes produced by normal cells, specifically glyoxalase I and II.  In contrast, harmful bacteria in alkaline environments are unable to detoxify MGO because they produce insufficient levels of glyoxalase required for MGO detoxification. Furthermore, MGO inactivates GA3PD (Glyceraldehyde 3-Phosphate Dehydrogenase), an enzyme essential for ATP production in the glycolytic  pathway. This inhibition prevents harmful bacteria from obtaining the energy necessary for growth and survival, ultimately leading to their death.

The antibacterial activity of the unique component MGO in Manuka honey is not yet fully understood from an academic perspective. However, a leading theory suggests that its selectivity is achieved by targeting the alkaline environments where harmful bacteria reside. Additionally, by eliminating harmful bacteria, an environment conducive to the growth of beneficial bacteria is created. As a result, this promotes  the proliferation of both beneficial bacteria and opportunistic bacteria that support them.

In this way, maintaining a healthy balance of gut bacteria under optimal conditions is extremely important for daily health management. The  high levels of MGO contained in this product help prevent exposure to harmful substances produced by harmful bacteria, such as various  toxins that contribute to the absorption of allergy-causing agents. This, in turn, strengthens immune cells and ultimately leads to improvements in overall health and constitution. While medications and cosmetics can be beneficial, it is even more important to enhance your natural healing power through a strong immune  system and to promote beauty from within the body. We highly recommend this product for use by your entire family.